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April 2012

Identifying Host Cell Genome Epitopes and What They Mean for Immunogenicity (invited talk – Annie De Groot and Lenny Moise)

4th Annual Tregitope Update: Baltimore (Following IIR Event)

Contact Curtis at CMillerIV@EpiVax.com to reserve a seat.

May 2012

 AAI Immunology 2012: Boston, MA, May 4-8, 2012

Tregitope Applications to Tolerance Induction in Autoimmune Diseases, Saturday, May 5, 10:15-12:15AM in the Hynes Convention Center Room 312. Oral and Poster #: P1565; Abstract #1337905

Tregitope Mechanism of Action and Applications for Tolerance Induction; Oral Presentation: Saturday, May 5, 10:15-12:15AM in the Hynes Convention Center Room 312. Poster #: P1569; Abstract #: 1337698

Regulating Immune Responses to Biologics: Epitope Prediction and Modulation. Poster #: P1153; Abstract #: 1338450

Invited Plenary IV: Tregitope: Applications to Tolerance induction in Autoimmune Disease. (De Groot, Cousens, et al.)

Tregitope mechanism of Action and Mechanism for Tolerance Induction. Abstract ID: 816 Oral Session. (De Groot, Cousens, et al.)

IgG-derived T cell epitopes (Tregitopes) suppress immune responses by activating nTregs.  (Yan Su, David Scott, others) Abstract ID: 852 Oral Session.

Tregitope suppression of anti-DNA mimotope immune responses. Scott et al.  Abstract ID: 853 Oral.

Tregitopes enhance regulatory T cell expansion and attenuate the autoimmune responses in a murine model of multiple sclerosis. Elyaman Khoury, et al.  Abstract ID: 748 Poster.

Adjuvant effects of C3d are mediated through the activation of C3d-specific autoreactive T cells. Messitt, De Groot, Knopf, et al. Abstract ID: 764 Oral.

AAPS NBC: San Diego, CA, May 20-24, 2012

Regulating Immune Responses to Biologics: Epitope Prediction and Applications. Poster #: M1035

Tregitope Applications to Tolerance Induction in Autoimmune Diseases. Poster #: W3002

Tregitope Mechanism of Action and Applications for Tolerance Induction. Poster #: W3001

Also in San Diego May 2012: Digestive Diseases Week May 19-22, 2012

AAV5 mediated delivery of Regulatory T-cell epitope 167 ameliorates acute experimental colitis and prevents a type 1 hypersensitivity reaction in a TNBS model of Crohn’s disease. Abstract ID: 1293819.

 June 2012

 Bio 2012 – Interactive Session – Panel on Immunogenicity

“Cutting Edge”: Making Better Biologics by Harnessing Tolerance and Immunogenicity”