Meet ISPRI 2.0
Say hello to ISPRI 2.0! – The ISPRI Toolkit is bigger and more beautiful, thanks to Matt Ardito and his team. ICYMI – ISPRI is the integrated, online, secure access version of our state-of the art tools for in silico immunogenicity screening and protein engineering. We recently embarked on a listening tour – getting your suggestions – and now – check out the results !
Immunogenicity Scales – In Multiple Flavors!
Want to compare your novel therapeutic sequences to relevant sequences of known immunogenicity? We have four new benchmark groups on the Protein Immunogenicity Scales. Choose from Pathogens, Autologous Proteins, Scaffold Proteins and Protein Therapeutics. Are there other benchmarks that you would like to see added? Let us know!
And now the Antibody Analysis silo has new scales too! Want to see the combined Tregitope-adjusted EpiMatrix score for submitted VH/VL sequences and the predicted ADA? Just toggle at the top:
And … Epitope Maps!
See an example Epitope Map below for Avastin’s variable heavy domain. Don’t you love it? This is my favorite new feature. Validated Tregitopes are highlighted in green and blue frames show potential T effector epitopes.
IYKYK – JanusMatrix Quadrant Plots!
The quadrant plot allows you to consider both the EpiMatrix score (HLA binding potential) and the JanusMatrix score (humanness) on the same visua
It’s MaGIC!
Stay tuned for the MaGIC Report – a Machine-Generated Immunogenicity Content snapshot that puts all of your data on one single print out!
Want access to ISPRI? Say hello to Riley Nolan, our ISPRI Client Liaison.
Register Now to Attend AI/HI!
Come join the party! Are you an ISPRI user? Or just curious? Come to the ISPRI User Workshop!
Save your spot – Sign up here!