Most Recent Publications Search T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation 08-2018 Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies. 04-2018 In Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01. 04-2018 Design, development and characterization of ACT017, a humanized Fab that blocks platelet’s glycoprotein VI function without causing bleeding risks. 04-2018 Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies. 04-2018 Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates. 04-2018 Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1. 04-2018 Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ. 04-2018 Activation of natural regulatory T cells by IgG Fc–derived peptide “Tregitopes” 02-2018 De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy 01-2018 Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics 12-2017 Circulating Normal IgG as Stimulator of Regulatory T Cells: Lessons from Intravenous Immunoglobulin 12-2017 « Older Entries Next Entries »
T-cell dependent immunogenicity of protein therapeutics: Preclinical assessment and mitigation 08-2018
Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies. 04-2018
In Silico and In Vitro Analysis of Interaction between Ximelagatran and Human Leukocyte Antigen (HLA)-DRB1*07:01. 04-2018
Design, development and characterization of ACT017, a humanized Fab that blocks platelet’s glycoprotein VI function without causing bleeding risks. 04-2018
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies. 04-2018
Harnessing a catalytic lysine residue for the one-step preparation of homogeneous antibody-drug conjugates. 04-2018
Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1. 04-2018
Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ. 04-2018
De-immunized and Functional Therapeutic (DeFT) versions of a long lasting recombinant alpha interferon for antiviral therapy 01-2018
Evaluating Immunogenicity Risk Due to Host Cell Protein Impurities in Antibody-Based Biotherapeutics 12-2017
Circulating Normal IgG as Stimulator of Regulatory T Cells: Lessons from Intravenous Immunoglobulin 12-2017
