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Identification and retrospective validation of T-cell epitopes in the hepatitis C virus genotype 4 proteome: An accelerated approach toward epitope-driven vaccine development

Identification and retrospective validation of T-cell epitopes in the hepatitis C virus genotype 4 proteome: An accelerated approach toward epitope-driven vaccine development

by Adam | Oct 22, 2016

Hum Vaccin Immunother. 2014 Jun 24;10(8). [Epub ahead of print] Full Text
An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8+ T cell epitopes

An immunoinformatic approach for identification of Trypanosoma cruzi HLA-A2-restricted CD8+ T cell epitopes

by Adam | Oct 22, 2016

Hum Vaccin Immunother. 2015;11(9):2322-8 .PMID: 26107442
Preclinical development of HIvax: human survivin Highly Immunogenic vaccines

Preclinical development of HIvax: human survivin Highly Immunogenic vaccines

by Adam | Oct 22, 2016

H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance

H7N9 T-cell epitopes that mimic human sequences are less immunogenic and may induce Treg-mediated tolerance

by Adam | Oct 22, 2016

iVAX: An integrated toolkit for the selection and optimization of antigens and the design of epitope-driven vaccines

iVAX: An integrated toolkit for the selection and optimization of antigens and the design of epitope-driven vaccines

by Adam | Jul 27, 2016

Computational vaccine design, also known as computational vaccinology, encompasses epitope mapping, antigen selection and immunogen design using computational tools. The iVAX toolkit is an integrated set of tools that has been in development since 1998 by De Groot and...
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  • Replacing Animal Models with Human-Relevant New Approach Methodologies (NAMs) for Immunogenicity in Clinic
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  • Immunogenicity Risk Assessment Outputs to Drive a Streamlined, Risk-Based Preclinical and Clinical Strategy
  • Immunogenicity Risk Assessment Outputs to Drive a Streamlined, Risk-Based Preclinical and Clinical Strategy

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