ISPRI Web-based Immunogenicity Screening
Interactive Screening and Protein Reengineering Interface – ISPRI
ISPRI is a secure, interactive work environment that is seamlessly linked to EpiVax’s proprietary in silico immunogenicity screening toolkit via the Internet. This interactive biologics optimization work environment gives your team access to the same in silico tools used by the EpiVax bioinformatics team. ISPRI can be used for high-throughput screening of partial and complete sequences of biological (protein therapeutic) candidates. The toolkit can identify potentially immunogenic regions (known as epitope clusters) within each protein sequence and map individual amino acids which contribute to the immunogenic potential of the cluster. The output is customized to best fit the needs and preferences of your biologics team.
The secure ISPRI environment can empower Researchers to:
The integration of the ISPRI system into the biologics discovery process and product development is a powerful proposition that will save time, money, and precious resources. ISPRI accelerates products toward clinical testing and the market. Applying the unique technologies in the ISPRI toolkit, such as EpiMatrix, ClustiMer, JanusMatrix, and OptiMatrix to new product candidates will increase the number of viable leads available for development, further enhancing the quality and value of an R&D pipeline.
ISPRI is a comprehensive service, available 24/7 with significant logistical and interpretation support from the EpiVax Bioinformatics team. Eight of the ten largest biopharma companies worldwide have adopted ISPRI as part of the R&D process.
Are you a small/mid-sized company with a small set of candidates? You might be more interested in our PreDeFT Reports.