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Matt Ardito (EpiVax IMF [immunoinformatics] team-member) did a quick analysis of the new Ebola sequences on Friday August 29th. He downloaded the newly published Ebolavirus GP proteins from GenBank. After loading the new sequences (from http://www.ncbi.nlm.nih.gov/bioproject/PRJNA257197) into IVAX, he selected the 16 original Ebola clusters that EpiVax immunoinformatician Guilhem Richard (IMF team-member) found in his original analysis and performed a local homology analysis against the 99 GP proteins. Of the 16 clusters, 13 are 100% conserved in the set of 99 Ebolavirus proteins. The remaining three sequences (SIPLGVIHNSTLQVSDVD, ESRFTPQFLLQLNETIYTSGK, andTEDHKIMASENSSAMVQ) have only 1 trivial mismatch.

See the following two websites for more information:

(1) New Ebola Sequences: http://www.ncbi.nlm.nih.gov/bioproject/PRJNA257197
(2) Our initial analysis: http://www.epivax.com/blog/ebola-extending-our-hand-to-help/